2,3,4,6-Tetra-O-acetyl-alpha-D-glucopyranosyl Bromide丨CAS 572-09-8

2,3,4,6-Tetra-O-acetyl-alpha-D-glucopyranosyl bromide丨CAS 572-09-8 is a protected glycosyl donor, widely used in carbohydrate chemistry and organic synthesis. It is a brominated sugar derivative where all hydroxyl groups on glucose are acetylated, and the anomeric position bears a bromide group. This configuration makes it highly reactive for glycosidation reactions, particularly in the synthesis of oligosaccharides, glycoproteins, and glycolipids.

1. Glycosylation Reagent (Donor)



2. Carbohydrate and Glycomimetic Synthesis

● Useful in pharmaceutical chemistry for the development of carbohydrate-based drugs or drug delivery systems.
3. Chemical Biology and Glycobiology


4. Intermediate for Modified Sugars
● Acts as a building block for modified glucose derivatives, including fluorinated, azido, or sulfur-substituted analogs, which are useful in metabolic labeling and bioconjugation.

1. High Reactivity and Selectivity


2. Versatility


3. Commercial Availability and Accessibility

2,3,4,6-Tetra-O-acetyl-alpha-D-glucopyranosyl bromide丨CAS 572-09-8 is a cornerstone reagent in the synthesis of glycosidic linkages and complex carbohydrate structures. Its balance of reactivity, selectivity, and ease of use makes it a go-to compound for researchers in the fields of glycochemistry, drug development, and bioconjugation. Whether used in assembling therapeutic oligosaccharides or designing glycoconjugate vaccines, this brominated sugar derivative remains indispensable in modern organic synthesis.